Implant-associated medication-related osteonecrosis of the jaw: pathophysiology and treatment
نویسندگان
چکیده
منابع مشابه
Medication-Related Osteonecrosis of the Jaw
Osteonecrosis of the jaw (ONJ) is a common side effect of antiresorptive drugs that are administered to cancer patients for bone metastasis, multiple myeloma, and osteoporosis. Since both bisphosphonate (BP) and denosumab show anti-bone resorption effects with ONJ, antiresorptive agent-related ONJ (ARONJ) has been suggested as a comprehensive term encompassing both BP-related osteonecrosis of t...
متن کاملFibrous Dysplasia and Medication-Related Osteonecrosis of the Jaw.
PURPOSE Osteonecrosis of the jaw (ONJ) is an established side effect of intravenous bisphosphonates and other antiresorptive medications. Although bisphosphonates are frequently prescribed for patients with the skeletal disorder fibrous dysplasia (FD), there are no reports of ONJ in this population. This has led some to conclude that patients with FD are at low risk for the development of bisph...
متن کاملBisphosphonate Associated Osteonecrosis of the Jaw: An Update on Pathophysiology, Risk Factors, and Treatment
Osteonecrosis of the jaw in patients treated with bisphosphonates is a relatively rare but well known complication at maxillofacial units around the world. It has been speculated that the medication, especially long-term i.v. bisphosphonate treatment, could cause sterile necrosis of the jaws. The aim of this narrative review of the literature was to elaborate on the pathological mechanisms behi...
متن کاملImplant failure associated with oral bisphosphonate-related osteonecrosis of the jaw
PURPOSE The aim of this study is to report a case of oral bisphosphonate-related osteonecrosis of the jaw (BRONJ) resulting in implant failure. METHODS A patient suspected of having BRONJ was referred to the Department of Periodontology, Kyung Hee University School of Dentistry for the evaluation and treatment of exposed bone around implants. RESULTS The patient, who had been taking oral bi...
متن کاملPerimandibular abscess associated with bisphosphonate‐related osteonecrosis of the jaw
1Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Kita-ku, Okayama-shi, Okayama, Japan 2Devision of Infection Control and Prevention, Osaka University Hospital, Suita-shi, Osaka, Japan 3Department of Oral and Maxillofacial Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Kita-ku,...
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ژورنال
عنوان ژورنال: International Journal of Oral and Maxillofacial Surgery
سال: 2017
ISSN: 0901-5027
DOI: 10.1016/j.ijom.2017.02.115